It happened at around 11:15 p.m. Thursday, April 14 in Melville.
Marie Louis, age 56, of North Amityville, was driving a 2005 Honda Civic westbound in the eastbound lanes of Express Drive South at Maxess Road, when the vehicle collided head-on with an eastbound 2021 Mercedes-Benz GLC, Suffolk County Police said.
Louis was transported to Nassau University Medical Center where she was pronounced dead, according to police.
The driver of the Mercedes driven by Venetia Atkinson, age 61, of North Baldwin, was transported to the same hospital for treatment of serious injuries.
Both vehicles were impounded.
Detectives are asking anyone with information on the crash to call the Second Squad at 631-854-8252.
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